Constipation Research - Infant, Child, Baby and Toddler Constipation, Symptoms, Causes, Remedies

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Medium-term results of vertical reduction rectoplasty and sigmoid colectomy for idiopathic megarectum.

Gladman MA, Williams NS, Scott SM, Ogunbiyi OA, Lunniss PJ

Centre for Academic Surgery (Gastrointestinal Physiology Unit), St Bartholomew's and The Royal London Hospital, Queen Mary's School of Medicine and Dentistry, Whitechapel, London, UK.

BACKGROUND: Vertical reduction rectoplasty (VRR) was devised specifically to address the physiological abnormalities present in the rectum of patients with idiopathic megarectum (IMR). This study evaluated the medium-term clinical and physiological results of VRR. METHODS: VRR and sigmoid colectomy was performed in ten patients with IMR and constipation (six women). Patients were evaluated before and a median of 60 (range 28-74) months after surgery by assessment of symptoms using scoring systems and anorectal physiological measurements. Independent, detailed postoperative evaluation of rectal diameter, compliance, and sensory and evacuatory function was performed. RESULTS: There were no deaths or late complications. Symptoms recurred necessitating permanent ileostomy formation in two patients. Median (range) constipation scores improved from 22 (18-27) before to 10 (0-24) after surgery (P = 0.016). Median (range) bowel frequency increased from 1.5 (0.2-7) to 7 (0.5-21) per week (P = 0.016). Rectal diameter, compliance and sensory function were normal in seven of eight patients after surgery. Evacuatory function and colonic transit were each normalized in two of eight patients after VRR. CONCLUSION: VRR corrected rectal diameter, compliance and sensory function in most patients, and clinical benefit was sustained in the medium term. The procedure was associated with a low morbidity, and no mortality and should be considered in the surgical management of IMR.

Published 2 May 2005 in Br J Surg, 92(5): 624-30.
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